Now showing items 1-7 of 7
Biological Evaluation of Some Uracil Derivatives as Potent Glutathione Reductase Inhibitors
(AMER INST PHYSICS, 2016)
Discovery of glutathione reductase (GR) inhibitors has become very popular recently due to antimalarial and anticancer activities. In this study, GR inhibitory capacities of some uracil derivatives (UDCs) (1-4) were reported. ...
Pyridazinone substituted benzenesulfonamides as potent carbonic anhydrase inhibitors
(PERGAMON-ELSEVIER SCIENCE LTD, 2016)
A series of sulfonamide derivatives (2a-l) incorporating substituted pyridazinone moieties were investigated for the inhibition of two human cytosolic carbonic anhydrase isoforms, hCA I and hCA II. All these compounds, ...
Kinetic and docking studies of cytosolic/tumor-associated carbonic anhydrase isozymes I, II and IX with some hydroxylic compounds
(TAYLOR & FRANCIS LTD, 2016)
A series of hydroxylic compounds (1-10, NK-154 and NK-168) have been assayed for the inhibition of three physiologically relevant carbonic anhydrase isozymes, the cytosolic isozymes I, II and tumor-associated isozyme IX. ...
Synthesis and Biological Evaluation of Novel Bischalcone Derivatives as Carbonic Anhydrase Inhibitors
(WILEY-V C H VERLAG GMBH, 2016)
Design and synthesis of a new type of bischalcones as an alternative to natural and synthetic bischalcones are reported for the first time. Key steps involved the solvent-free Claisen-Schmidt condensation of chalcones, and ...
Investigation of Inhibitory Effects of Some Sulfonamides on Acethylcholinesterase Enzyme